Ben Laufer
Ben Laufer

Principal Scientist

Genentech

About

Ben Laufer is a computational biologist who researches gene expression and neuroscience. He is a Principal Scientist in the Neuroinformatics group at Genentech.

Interests
  • Bioinformatics
  • Gene Regulation
  • Neuroscience
Education

  • Postdoctoral Fellowship

    University of California Davis, USA

  • PhD in Cellular & Molecular Biology

    Western University, Canada

  • BSc (Hons) in Genetics

    Western University, Canada

Recent Publications
Sara L Dominguez, Benjamin I Laufer, Arundhati Sengupta Ghosh, Qingling Li, Gaia Ruggeri, Maheswara Reddy Emani, Lilian Phu, Brad a Friedman, Wendy Sandoval, Christopher M Rose, Hai Ngu, Oded Foreman, Mike Reichelt, Yves Juste, Guita Lalehzadeh, Dennis Hansen, Helle Nymark, Denia Mellal, Helene Gylling, Łukasz J Kiełpiʼnski, Ben Chih, Baris Bingol, Casper C Hoogenraad, William J Meilandt, Amy Easton (2023). TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models. iScience.
DOI
Amy E. Byrnes, Sara L. Dominguez, Chun-Wan Yen, Benjamin I. Laufer, Oded Foreman, Mike Reichelt, Han Lin, Meredith Sagolla, Kathy Hötzel, Hai Ngu, Christoffer Soendergaard, Alberto Estevez, Hsiu-Chao Lin, Alexandre Goyon, Juan Bian, Jessica Lin, Flora I. Hinz, Brad A. Friedman, Amy Easton, Casper C. Hoogenraad (2023). Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection. Molecular Therapy — Nucleic Acids.
DOI
Min Jung, Michelle Dourado, James Maksymetz, Amanda Jacobson, Benjamin I. Laufer, Miriam Baca, Oded Foreman, David H. Hackos, Lorena Riol-Blanco, Joshua S. Kaminker (2023). Cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function. Nature Communications.
DOI
Benjamin I. Laufer, Yu Hasegawa, Zhichao Zhang, Casey E. Hogrefe, Laura A. Del Rosso, Lori Haapanen, Hyeyeon Hwang, Melissa D. Bauman, Judy Van De Water, Ameer Y. Taha, Carolyn M. Slupsky, Mari S. Golub, John P. Capitanio, Catherine A. VandeVoort, Cheryl K. Walker, Janine M. Lasalle (2022). Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models. Nature Communications.
DOI
Shristi Pandey, Kimberle Shen, Seung-Hye Lee, Yun-an A. Shen, Yuanyuan Wang, Marcos Otero-Garcı́a, Natalya Kotova, Stephen T. Vito, Benjamin I. Laufer, Dwight F. Newton, Mitchell G. Rezzonico, Jesse E. Hanson, Joshua S. Kaminker, Christopher J. Bohlen, Tracy J. Yuen, Brad A. Friedman (2022). Disease-associated oligodendrocyte responses across neurodegenerative diseases. Cell Reports.
DOI
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