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Latest

• Publications
• Multiplex screening of transferrin receptor-targeted lipid nanoparticles for systemic brain delivery using DNA barcodes
• Predictive in vitro profiling of LNP-induced innate immune response using an iPSC-derived monocyte model
• Integrated Cross-Disease Atlas of Human And Mouse Astrocytes Reveals Heterogeneity and Conservation of Astrocyte Subtypes in Neurodegeneration
• TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models
• Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection
• Cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function
• Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models
• Elevated exposures to persistent endocrine disrupting compounds impact the sperm methylome in regions associated with autism spectrum disorder
• Disease-associated oligodendrocyte responses across neurodegenerative diseases