Publications

Soumitra Ghosh, Yuchen Fan, Benjamin I. Laufer, William Stephenson, Nanzhi Zang, Jessica Lawrence, Han H. Lin, Sanjana Sen, Stephen E. Miller, Sarah Chu, Jose Imperio, Eric Lubeck, Chun-Wan Yen, William J. Meilandt, Stephanie Monson, Baris Bingol, Brad A. Friedman, Whitney Shatz-Binder (2025). Multiplex screening of transferrin receptor-targeted lipid nanoparticles for systemic brain delivery using DNA barcodes. Cell Biomaterials.
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Baixue Xiao, Soojin Kim, Benjamin I. Laufer, Anthony Antonelli, Milena Hornburg, Divya Murali, Yimin Gu, Pierce Jessen, Diamanda Rigas, Rebecca Leylek, Keiko Hokeness, Emily Freund, Eric Torres, Gaia Ruggeri, Siri Tahtinen, Yuchen Fan, Chun-Wan Yen, Maheswara Reddy Emani (2025). Predictive in vitro profiling of LNP-induced innate immune response using an iPSC-derived monocyte model. bioRxiv.
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Tawaun A. Lucas, Gloriia Novikova, Sadhna Rao, Yuanyuan Wang, Benjamin I. Laufer, Shristi Pandey, Michelle G. Webb, Nikolas Jorstad, Brad A. Friedman, Jesse E. Hanson, Joshua S. Kaminker (2025). Integrated Cross-Disease Atlas of Human And Mouse Astrocytes Reveals Heterogeneity and Conservation of Astrocyte Subtypes in Neurodegeneration. bioRxiv.
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Sara L. Dominguez, Benjamin I. Laufer, Arundhati Sengupta Ghosh, Qingling Li, Gaia Ruggeri, Maheswara Reddy Emani, Lilian Phu, Brad A. Friedman, Wendy Sandoval, Christopher M. Rose, Hai Ngu, Oded Foreman, Mike Reichelt, Yves Juste, Guita Lalehzadeh, Dennis Hansen, Helle Nymark, Denia Mellal, Helene Gylling, Łukasz J. Kiełpiʼnski, Ben Chih, Baris Bingol, Casper C. Hoogenraad, William J. Meilandt, Amy Easton (2023). TMEM106B reduction does not rescue GRN deficiency in iPSC-derived human microglia and mouse models. iScience.
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Amy E. Byrnes, Sara L. Dominguez, Chun-Wan Yen, Benjamin I. Laufer, Oded Foreman, Mike Reichelt, Han Lin, Meredith Sagolla, Kathy Hötzel, Hai Ngu, Christoffer Soendergaard, Alberto Estevez, Hsiu-Chao Lin, Alexandre Goyon, Juan Bian, Jessica Lin, Flora I. Hinz, Brad A. Friedman, Amy Easton, Casper C. Hoogenraad (2023). Lipid nanoparticle delivery limits antisense oligonucleotide activity and cellular distribution in the brain after intracerebroventricular injection. Molecular Therapy — Nucleic Acids.
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Min Jung, Michelle Dourado, James Maksymetz, Amanda Jacobson, Benjamin I. Laufer, Miriam Baca, Oded Foreman, David H. Hackos, Lorena Riol-Blanco, Joshua S. Kaminker (2023). Cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function. Nature Communications.
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Benjamin I. Laufer, Yu Hasegawa, Zhichao Zhang, Casey E. Hogrefe, Laura A. Del Rosso, Lori Haapanen, Hyeyeon Hwang, Melissa D. Bauman, Judy Van De Water, Ameer Y. Taha, Carolyn M. Slupsky, Mari S. Golub, John P. Capitanio, Catherine A. VandeVoort, Cheryl K. Walker, Janine M. LaSalle (2022). Multi-omic brain and behavioral correlates of cell-free fetal DNA methylation in macaque maternal obesity models. Nature Communications.
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Angela G. Maggio, Henry T. Shu, Benjamin I. Laufer, Chongfeng Bi, Yinglei Lai, Janine M. LaSalle, Valerie W. Hu (2022). Elevated exposures to persistent endocrine disrupting compounds impact the sperm methylome in regions associated with autism spectrum disorder. Frontiers in Genetics.
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Shristi Pandey, Kimberle Shen, Seung-Hye Lee, Yun-an A. Shen, Yuanyuan Wang, Marcos Otero-Garcı́a, Natalya Kotova, Stephen T. Vito, Benjamin I. Laufer, Dwight F. Newton, Mitchell G. Rezzonico, Jesse E. Hanson, Joshua S. Kaminker, Christopher J. Bohlen, Tracy J. Yuen, Brad A. Friedman (2022). Disease-associated oligodendrocyte responses across neurodegenerative diseases. Cell Reports.
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Benjamin I. Laufer, Kari Neier, Anthony E. Valenzuela, Dag H. Yasui, Rebecca J. Schmidt, Pamela J. Lein, Janine M. LaSalle (2022). Placenta and fetal brain share a neurodevelopmental disorder DNA methylation profile in a mouse model of prenatal PCB exposure. Cell Reports.
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