"Down syndrome"

Stable DNMT3L overexpression in SH-SY5Y neurons recreates a facet of the genome-wide Down syndrome DNA methylation signature
Background: Down syndrome (DS) is characterized by a genome-wide profile of differential DNA methylation that is skewed towards …
Benjamin I. Laufer, J. Antonio Gomez, Julia M. Jianu, Janine M. LaSalle
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Whole genome bisulfite sequencing of Down syndrome brain reveals regional DNA hypermethylation and novel disorder insights
Down Syndrome (DS) is the most common genetic cause of intellectual disability, in which an extra copy of human chromosome 21 (HSA21) …
Benjamin I. Laufer, Hyeyeon Hwang, Annie Vogel Ciernia, Charles E. Mordaunt, Janine M. LaSalle
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