"Fetal alcohol spectrum disorders"

Associative DNA methylation changes in children with prenatal alcohol exposure
Aim: Prenatal alcohol exposure (PAE) can cause fetal alcohol spectrum disorders (FASD). Previously, we assessed PAE in brain tissue …
Benjamin I. Laufer, Joachim Kapalanga, Christina A. Castellani, Eric J. Diehl, Liying Yan, Shiva M. Singh
PDF Cite Project DOI
Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: A model for fetal alcohol spectrum disorders
There is abundant evidence that prenatal alcohol exposure leads to a range of behavioral and cognitive impairments, categorized under …
Morgan L. Kleiber, Eric J. Diehl, Benjamin I. Laufer, Katarzyna Mantha, Aniruddho Chokroborty-Hoque, Bonnie Alberry, Shiva M. Singh
PDF Cite DOI
Third trimester-equivalent ethanol exposure is characterized by an acute cellular stress response and an ontogenetic disruption of genes critical for synaptic establishment and function in mice
The developing brain is remarkably sensitive to alcohol exposure, resulting in the wide range of cognitive and neurobehavioral …
Morgan L. Kleiber, Benjamin I. Laufer, Randa L. Stringer, Shiva M. Singh
PDF Cite DOI
Long-lasting alterations to DNA methylation and ncRNAs could underlie the effects of fetal alcohol exposure in mice
Fetal alcohol spectrum disorders (FASDs) are characterized by life-long changes in gene expression, neurodevelopment and behavior. What …
Benjamin I. Laufer, Katarzyna Mantha, Morgan L. Kleiber, Eric J. Diehl, Sean M.F. Addison, Shiva M. Singh
PDF Cite Project DOI