2

Alteration of gene expression, DNA methylation, and histone methylation in free radical scavenging networks in adult mouse hippocampus following fetal alcohol exposure
The molecular basis of Fetal Alcohol Spectrum Disorders (FASD) is poorly understood; however, epigenetic and gene expression changes …
Eric J. Chater-Diehl, Benjamin I. Laufer, Christina A. Castellani, Bonnie L. Alberry, Shiva M. Singh
PDF Cite DOI
Strategies for precision modulation of gene expression by epigenome editing: An overview
Genome editing technology has evolved rather quickly and become accessible to most researchers. It has resulted in far reaching …
Benjamin I. Laufer, Shiva M. Singh
PDF Cite DOI
Associative DNA methylation changes in children with prenatal alcohol exposure
Aim: Prenatal alcohol exposure (PAE) can cause fetal alcohol spectrum disorders (FASD). Previously, we assessed PAE in brain tissue …
Benjamin I. Laufer, Joachim Kapalanga, Christina A. Castellani, Eric J. Diehl, Liying Yan, Shiva M. Singh
PDF Cite Project DOI
DNA methylation differences in monozygotic twin pairs discordant for schizophrenia identifies psychosis related genes and networks
Background: Despite their singular origin, monozygotic twin pairs often display discordance for complex disorders including …
Christina A. Castellani, Benjamin I. Laufer, Melkaye G. Melka, Eric J. Diehl, Richard L. O'Reilly, Shiva M. Singh
PDF Cite DOI
DNA methylation in psychosis: Insights into etiology and treatment
Evidence for involvement of DNA methylation in psychosis forms the focus of this perspective. Of interest are results from two …
Christina A. Castellani, Melkaye G. Melka, Eric J. Diehl, Benjamin I. Laufer, Richard L. O'Reilly, Shiva M. Singh
PDF Cite DOI
Fetal alcohol and the right to be born healthy
Shiva M. Singh, Benjamin I. Laufer, Joachim Kapalanga
PDF Cite DOI
Long-term genomic and epigenomic dysregulation as a consequence of prenatal alcohol exposure: A model for fetal alcohol spectrum disorders
There is abundant evidence that prenatal alcohol exposure leads to a range of behavioral and cognitive impairments, categorized under …
Morgan L. Kleiber, Eric J. Diehl, Benjamin I. Laufer, Katarzyna Mantha, Aniruddho Chokroborty-Hoque, Bonnie Alberry, Shiva M. Singh
PDF Cite DOI
Molecular changes during neurodevelopment following second-trimester binge ethanol exposure in a mouse model of fetal alcohol spectrum disorder: From immediate effects to long-term adaptation
Fetal alcohol spectrum disorder (FASD) is an umbrella term that refers to a wide range of behavioral and cognitive deficits resulting …
Katarzyna Mantha, Benjamin I. Laufer, Shiva M. Singh
PDF Cite DOI
The effects of olanzapine on genome-wide DNA methylation in the hippocampus and cerebellum
Background: The mechanism of action of olanzapine in treating schizophrenia is not clear. This research reports the effects of a …
Melkaye G. Melka, Benjamin I. Laufer, Patrick McDonald, Christina A. Castellani, Nagalingam Rajakumar, Richard O'Reilly, Shiva M. Singh
PDF Cite DOI
Third trimester-equivalent ethanol exposure is characterized by an acute cellular stress response and an ontogenetic disruption of genes critical for synaptic establishment and function in mice
The developing brain is remarkably sensitive to alcohol exposure, resulting in the wide range of cognitive and neurobehavioral …
Morgan L. Kleiber, Benjamin I. Laufer, Randa L. Stringer, Shiva M. Singh
PDF Cite DOI